Migraine in women is linked with cardiovascular disease
1 Comment Published by JonMikel, M.D. July 18th, 2006 in News, Medical JournalVia JAMA. 2006;296:283-291.
Migraine with aura is associated with increased risk of major cardiovascular disease (CVD), myocardial infarction, ischemic stroke, and death due to ischemic CVD, coronary revascularization and angina. Active migraine without aura was not associated with increased risk of any CVD event.
This prospective cohort-type study enrolled 27,840 women aged 45 years or older who were participating in the Women’s Health Study, were free of CVD and angina at study entry (1992-1995), and who had information on self-reported migraine and aura status, and lipid measurements. This report is based on follow-up data through March 2004.
At baseline, 5125 women (18.4%) reported any history of migraine; of the 3610 with active migraine (migraine in the prior year), 1434 (39.7%) indicated aura symptoms.
During a mean of 10 years of follow-up, 580 major CVD events occurred. Compared with women with no migraine history, women who reported active migraine with aura had multivariable-adjusted hazard ratios of 2.15 (95% confidence interval [CI], 1.58-2.92; P<.001) for major CVD, 1.91 (95% CI, 1.17-3.10; P = .01) for ischemic stroke, 2.08 (95% CI, 1.30-3.31; P = .002) for myocardial infarction, 1.74 (95% CI, 1.23-2.46; P = .002) for coronary revascularization, 1.71 (95% CI, 1.16-2.53; P = .007) for angina, and 2.33 (95% CI, 1.21-4.51; P = .01) for ischemic CVD death.
After adjusting for age, there were 18 additional major CVD events attributable to migraine with aura per 10 000 women per year. Women who reported active migraine without aura did not have increased risk of any vascular events or angina.
It will be nice when a novel study evaluates the prevention (triptans, ASA, beta-blockers) of this association between migraine with aura and CVD.
Link to: Acetaminophen + aspirin + caffeine to treat acute attacks of migraine
Regards,
Jon Mikel Iñarritu, M.D.
Yesterday at Health-Hack.com they made a list of six of the most evident symptoms of some serious illness, via WebMD:
From WebMD:
1. If you have unexplained weight loss and/or loss of appetite, you may have a serious underlying medical illness.
2. Slurred speech, paralysis, weakness, tingling, burning pains, numbness, and confusion are signs of a stroke, and you should get to an appropriate emergency center immediately. Early treatment may prevent permanent damage to the brain or even save your life.
3. Black, tarry stools may indicate a hemorrhage from an ulcer of the stomach or the intestine. It is important to stop the bleeding and to rule out cancer as a cause.
4. A headache accompanied by a stiff neck and fever is an indicator of a serious infection called meningitis.
5. A sudden, agonizing headache, more severe than any you have felt before, could mean you are bleeding in the brain. Go to an emergency room immediately.
6. For women: Vaginal bleeding after menopause is a waning sign of possible cancer.
6. For men: A lump in your testicle with or without a small lump in the groin could be serious. Testicular cancer is more commonly found in testicles that did not naturally descend from the abdomen to the scrotum.
Via Lifehacker.com
